Hematology data from in vivo toxicology studies remains one of the most predictive measures for human risk, as the same measurements made in pre-clinical toxicology studies can be made in early clinical trials. Covering the three main blood cell types – erythrocytes, leukocytes and thrombocytes, Animal Hematotoxicology: A Practical Guide for Toxicologists and Biomedical Researchers is designed to clarify topics to the fields of laboratory animal hematology and toxicology, especially those topics where the rules for human hematology do not always apply. An entire chapter is devoted to immunotoxicology, a scientific discipline that is closely aligned with hematology. The text also addresses pre-analytical and analytical variables that affect animal studies, as these play a far more important part when interpreting data in contrast to humans where many of these variables can be well controlled or have less physiological effect. 221 p.
- G. O. Evans, Former principal clinical chemist at Birmingham Children’s Hospital (Englanc), Laboratory animal toxicology and clinical pathology specialist, Former Head of clinical pathology at Wellcome Research Laboratories, Beckenham (England), Former Director of clinical pathology at Astra Charnwood, and later the two AstraZeneca sites in the United Kingdom, Currently Director of A. George Owen and Company.
- Publication date (print): 2009-07
- ISBN (print): 978‑1‑4200‑8009‑4