Following a short historical introduction and a discussion of the ethics surrounding animal experiments, the book describes correct study design as well as the handling and housing of animals. It then goes on to describe the animal models available for different cancer types, from natural cancer models in mice and dogs to humanized animals. An evaluation of previously unpublished long-term data from the Swiss canine and feline cancer registry is also included. The final part of the book reviews the lessons learned over the last decade on how to interpret data from animal studies for improving human therapy and gives recommendations for future drug development. 271 p.
- Marianne I. Martic-Kehl, Editor. Senior Assistant. Transdisciplinary Laboratorium Collegium Helveticum, a joint institution of the Swiss Federal Institute of Technolgy (ETH) and the University of Zurich (UZH).
- P. August Schubiger, Editor. Senior fellow, currently involved in the project 'Drug development - significance and predictive value of animal testing'. Transdisciplinary Laboratorium Collegium Helveticum, a joint institution of the Swiss Federal Institute of Technolgy (ETH) and the University of Zurich (UZH).
- publication date (print): 2016-07
- ISBN (print): 978-3-527-33997-6
- ISBN (ebook PDF): 978-3-527-69591-1